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  2. Clar's rule - Wikipedia

    en.wikipedia.org/wiki/Clar's_rule

    Fusing angular rings around a benzene moiety leads to an increase in stability. The Clar structure of anthracene , for instance, has only one π-sextet but, by moving one ring into the angular position, phenanthrene is obtained, the Clar structure of which carries two circles instead of one.

  3. Hückel's rule - Wikipedia

    en.wikipedia.org/wiki/Hückel's_rule

    The best-known example is benzene (C 6 H 6) with a conjugated system of six π electrons, which equals 4n + 2 for n = 1. The molecule undergoes substitution reactions which preserve the six π electron system rather than addition reactions which would destroy it. The stability of this π electron system is referred to as aromaticity. Still, in ...

  4. Ortho effect - Wikipedia

    en.wikipedia.org/wiki/Ortho_effect

    There are three main ortho effects in substituted benzene compounds: Steric hindrance forces cause substitution of a chemical group in the ortho position of benzoic acids become stronger acids. Steric inhibition of protonation caused by substitution of anilines to become weaker bases, compared to substitution of isomers in the meta and para ...

  5. Benzene - Wikipedia

    en.wikipedia.org/wiki/Benzene

    As benzene is ubiquitous in gasoline and hydrocarbon fuels that are in use everywhere, human exposure to benzene is a global health problem. Benzene targets the liver, kidney, lung, heart and brain and can cause DNA strand breaks and chromosomal damage, hence is teratogenic and mutagenic. Benzene causes cancer in animals including humans.

  6. Solvent effects - Wikipedia

    en.wikipedia.org/wiki/Solvent_effects

    Water, being the most polar-solvent listed above, stabilizes the ionized species to a greater extent than does DMSO or Acetonitrile. Ionization - and, thus, acidity - would be greatest in water and lesser in DMSO and Acetonitrile, as seen in the table below, which shows p K a values at 25 °C for acetonitrile (ACN) [ 2 ] [ 3 ] [ 4 ] and ...

  7. Chemical stability - Wikipedia

    en.wikipedia.org/wiki/Chemical_stability

    In chemistry, chemical stability is the thermodynamic stability of a chemical system, in particular a chemical compound or a polymer. [ 1 ] Thermodynamic stability occurs when a system is in its lowest energy state , or in chemical equilibrium with its environment.

  8. Aromaticity - Wikipedia

    en.wikipedia.org/wiki/Aromaticity

    Two different resonance forms of benzene (top) combine to produce an average structure (bottom). In organic chemistry, aromaticity is a chemical property describing the way in which a conjugated ring of unsaturated bonds, lone pairs, or empty orbitals exhibits a stabilization stronger than would be expected by the stabilization of conjugation alone.

  9. Resonance (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Resonance_(chemistry)

    Contributing structures of the carbonate ion. In chemistry, resonance, also called mesomerism, is a way of describing bonding in certain molecules or polyatomic ions by the combination of several contributing structures (or forms, [1] also variously known as resonance structures or canonical structures) into a resonance hybrid (or hybrid structure) in valence bond theory.