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2. Niacin - Wikipedia

   en.wikipedia.org/wiki/Niacin

   A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]

3. Statin - Wikipedia

   en.wikipedia.org/wiki/Statin

   Combining any statin with a fibrate or niacin (other categories of lipid-lowering drugs) increases the risks for rhabdomyolysis to almost 6.0 per 10,000 person-years ...

4. Colesevelam - Wikipedia

   en.wikipedia.org/wiki/Colesevelam

   The statins are considered the first-line agents. This is because of the larger body of evidence supporting statins' ability to prevent cardiovascular disease, as well as the prominent side effects from the other two types, including bloating and constipation (bile-acid sequestrants) and skin flushing (niacin).

5. How to eat your way to lower cholesterol

   www.aol.com/eat-way-lower-cholesterol-140000906.html

   For example, Hensrud advised against using niacin, which lowers cholesterol but has side effects, among them flushing. It also can raise liver enzymes when taken in large doses, Hensrud said ...

6. A cholesterol-lowering alternative to statins reduces deaths ...

   www.aol.com/news/cholesterol-lowering...

   An alternative to statins may help reduce deaths from heart disease among people with high levels of LDL, or “bad” cholesterol, new research finds.. When taken as a daily pill, bempedoic acid ...

7. AIM-HIGH (trial) - Wikipedia

   en.wikipedia.org/wiki/AIM-HIGH_(trial)

   Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes (also known as AIM-HIGH) was a randomized control trial designed to assess the efficacy of niacin (extended-release) added to statin therapy in reducing cardiovascular events in patients with established atherosclerotic cardiovascular disease (ASCVD).