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Diabetic dermadromes constitute a group of cutaneous conditions commonly seen in people with diabetes with longstanding disease. [1] Conditions included in this group are: [1] [2] Acral dry gangrene; Carotenosis; Diabetic dermopathy; Diabetic bulla; Diabetic cheiroarthropathy; Malum perforans; Necrobiosis lipoidica
Diabetic dermopathy is a type of skin lesion usually seen in people with diabetes mellitus.It is characterized by dull-red papules that progress to well-circumscribed, small, round, atrophic hyperpigmented skin lesions usually on the shins.
Diabetic cheiroarthropathy, also known as diabetic stiff hand syndrome or limited joint mobility syndrome, is a cutaneous condition characterized by waxy, thickened skin and limited joint mobility of the hands and fingers, leading to flexion contractures, a condition associated with diabetes mellitus [1]: 681 and it is observed in roughly 30% of diabetic patients with longstanding disease.
Glucose is a simple sugar and the primary fuel for body cells. It is absorbed from some foods (or produced from starchy ones), absorbed into the cells (for about 2/3 of cells, this is under control of insulin), stored temporarily in the liver as glycogen, made in starvation from the glycerin backbone of triglycerides, and from a few amino acids.
Dermopathy can refer to one of several diseases: Diabetic dermopathy; Graves' dermopathy, or infiltrative dermopathy; Nephrogenic fibrosing dermopathy (NFD)
A diabetic bulla, also known as bullosis diabeticorum, or bullous eruption of diabetes mellitus, is a cutaneous condition characterized by a noninflammatory, spontaneous, painless blister, often in acral locations (peripheral body parts, such as feet, toes, hands, fingers, ears or nose), seen in diabetic patients. [2] [3]: 681 [3]: 467–8
Micrograph showing contraction band necrosis, a histopathologic finding of myocardial infarction (heart attack).. Histopathology (compound of three Greek words: ἱστός histos 'tissue', πάθος pathos 'suffering', and -λογία-logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease.
In diabetic patient's, levels of the hepatocyte growth factor (HGF) were found in high levels, thus independently associated with increased the incidence of diabetes. There is a study that indicate that HGF/c-Met signalling is essential for maternal β-cell adaptation during pregnancy and that its absence/attenuation leads to gestational ...