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  2. Empagliflozin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin

    Empagliflozin, sold under the brand name Jardiance (/ ˈ dʒ ɑːr d i ə n s / JAR-dee-əns), among others, is an antidiabetic medication used to improve glucose control in people with type 2 diabetes. [12] [2] [14] It is taken by mouth. [2]

  3. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    The mechanism of action on a cellular level is not well understood. Work is underway to define this mechanism as a prodiuretic with great promise. However, it has been shown that binding of different sugars to the glucose site affects the orientation of the aglycone in the access vestibule. So when the aglycone binds it affects the entire ...

  4. Meglitinide - Wikipedia

    en.wikipedia.org/wiki/Meglitinide

    Mechanism of action [ edit ] They bind to an ATP -dependent K + (K ATP ) channel on the cell membrane of pancreatic beta cells in a similar manner to sulfonylureas but have a weaker binding affinity and faster dissociation from the SUR1 binding site.

  5. Biden administration says Medicare negotiated price discounts ...

    www.aol.com/biden-administration-says-medicare...

    The Biden administration said Medicare negotiated discounts with pharmaceutical companies on 10 drugs prescribed to treat cancer and heart disease.

  6. Zepbound Weight Loss Medication Approved by FDA to Treat ...

    www.aol.com/fda-approves-weight-loss-medication...

    The weight loss drug Zepbound, generically known as tirzepatide, is also now an approved medication to treat obstructive sleep apnea, per a Food and Drug Administration Dec. 20 press release.. The ...

  7. Dapagliflozin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin

    Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment

  8. Sitagliptin - Wikipedia

    en.wikipedia.org/wiki/Sitagliptin

    It is taken by mouth. [8] It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet, Janumet XR). [8] Common side effects include headaches, swelling of the legs, and upper respiratory tract infections. [8] Serious side effects may include angioedema, low blood sugar, kidney problems, pancreatitis, and joint ...

  9. Tirzepatide - Wikipedia

    en.wikipedia.org/wiki/Tirzepatide

    Novo Nordisk has taken action against several compounding pharmacies producing bad versions of the drug, with impurities, the wrong amount of active ingredient, or even no active ingredient. [60] Some compounded versions have been found to contain salts of semaglutide including the sodium and the acetate in an attempt to avoid the patent of the ...

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