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Medication administered via intramuscular injection is not subject to the first-pass metabolism effect which affects oral medications. Common sites for intramuscular injections include the deltoid muscle of the upper arm and the gluteal muscle of the buttock. In infants, the vastus lateralis muscle of the thigh is commonly used. The injection ...
The most common site of insertion is the antero-medial aspect of the upper, proximal tibia as this site lies just under the skin and is easily located. Other insertion sites include the anterior aspect of the femur , the superior iliac crest, proximal humerus , proximal tibia, distal tibia and the sternum (manubrium). [ 1 ]
However, in common English the term has mostly been used to describe the four most well-known routes of injection. A peripheral IV placed on the hand. A medical professional performs an intradermal (ID) injection. The term injection encompasses intravenous (IV), intramuscular (IM), subcutaneous (SC) and intradermal (ID) administration. [35]
The two techniques Travell described are the injection of a local anesthetic and the mechanical use of a hypodermic needle without injecting a solution. [8] Travell preferred a, 1.5-in hypodermic needle for trigger point therapy and used this needle for both injection therapy and dry needling. Travell never used an acupuncture needle.
The spread of HIV, Hepatitis B, and Hepatitis C from injection drug use is a common health problem, [37] in particular contributing to over half of new HIV cases in North America in 1994. [7] Other infections may occur when pathogens enter the body through the injection site, most commonly due to improper cleaning of the site before injection.
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...
For many biologics (e.g., monoclonal antibodies), injection site reactions are the most common adverse effect of the drug, and have been reported to have an incidence rate of 0.5–40%. [ 2 ] In trials of subcutaneous administration of oligonucleotides , between 22 and 100% of subjects developed reactions depending on the oligonucleotide.
CICs are administered by intramuscular injection into the deltoid, gluteus maximus, or anterior thigh. [1] They are ideally administered every 28 to 30 days, though they have been demonstrated to be effective up to 33 days. [1] Some CICs have been said to be used by transgender women as a means of feminizing hormone therapy as well. [12]