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Nasal polyps resulting from chronic rhinosinusitis affect approximately 4.3% of the population. [6] Nasal polyps occur more frequently in men than women and are more common as people get older, increasing drastically after the age of 40. [6] Of people with chronic rhinosinusitis, 10% to 54% also have allergies.
Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
Max Samter (March 8, 1909 – February 9, 1999) was a German-American immunologist who first extensively studied the triad between asthma, aspirin allergy, and nasal polyps that became known as Samter's triad, now aspirin-exacerbated respiratory disease. [1] Samter was a third generation doctor and obtained medical training in Europe. [2]
Asthma and other breathing difficulties; Polyps with asthma; Angioedema; Rhinitis, sinusitis, nasal polyps; Asthma and nasal polyps are also symptoms of aspirin-exacerbated respiratory disease (AERD, Samter's Triad), which is not believed to be caused by dietary salicylates.
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It can be caused by anatomical factors such as a deviated septum or nasal polyps (growths), as well as infection. Symptoms include difficulty breathing through the nose, swelling and pain around the nose and eyes, postnasal drainage down the throat, and difficulty sleeping. [10] CRS is a common condition in children and young adults. [11]
Stridor is a high-pitched sound which occurs during breathing and is associated with obstruction at the level of the larynx. Difficulty swallowing and changes in voice are also common symptoms. [ 3 ] If there is total obstruction, severe respiratory distress or cyanosis due to hypoxia (lack of oxygen in the blood) can occur.
Nasal surgery is a specialty including the removal of nasal obstruction that cannot be achieved by medication and nasal reconstruction. Currently, it comprises four approaches, namely rhinoplasty, septoplasty, sinus surgery, and turbinoplasty, targeted at different sections of the nasal cavity in the order of their external to internal positions.
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