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Congenital contractural arachnodactyly (CCA), also known as Beals–Hecht syndrome, is a rare autosomal dominant congenital connective tissue disorder. [1] As with Marfan syndrome , people with CCA typically have an arm span that is greater than their height and very long fingers and toes . [ 2 ]
In pathology, a contracture is a shortening of muscles, tendons, skin, and nearby soft tissues that causes the joints to shorten and become very stiff, preventing normal movement. [ 1 ] [ 2 ] A contracture is usually permanent, but less commonly can be temporary (such as in McArdle disease ), [ 3 ] or resolve over time but reoccur later in life ...
Dupuytren's contracture of the right little finger. Arrow marks the area of scarring. Typically, Dupuytren's contracture first presents as a thickening or nodule in the palm, which initially can be with or without pain. [11] Later in the disease process, which can be years later, [12] there is increasing loss of range of motion of the affected ...
Bethlem myopathy 1 is a rare disease, affecting about 1 in 200,000 people. [8] Bethlem myopathy 2 is an ultra-rare disease, affecting less than 1 in 1,000,000 people. [9] The condition was described by J. Bethlem and G. K. van Wijngaarden in 1976. [10]
Adhesions and fibrosis are made of dense fibrous tissue, which are strong and supportive, helping to prevent the injury or micro-injury from reoccurring. However, the fibrotic scar tissue causes the muscle tissue to become stuck together which restricts movement, causing pain, weakness, and limited joint mobility. [15] [16] [17] [18]
The average life expectancy in the U.S. is 77.5 years, according to the Centers for Disease Control and Prevention. But Americans outlive their health spans by 12.4 years, the study found.
[4] [16] As a result of frequent tissue injury, there can be an early onset of advanced osteoarthritis, [45] chronic degenerative joint disease, [45] swan-neck deformity of the fingers, [46] and Boutonniere deformity of the fingers. Tendon and ligament laxity offer minuscule protection from tearing in muscles and tendons, but these problems ...
From 2019 to 2021, U.S. life expectancy dropped from 78.8 years to 7 6.4. Covid deaths fell significantly last year: Whereas Covid was the fourth leading cause of death in 2022, it was the 10th in ...