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  2. Urinary anti-infective agent - Wikipedia

    en.wikipedia.org/wiki/Urinary_anti-infective_agent

    The discovery of antimicrobial agents contributed significantly to UTI management during the 20th century. Nitrofurantoin emerged as the first practical and safe urinary antimicrobial agent, but it was with limited spectrum of activity. [48] Subsequently, in the 1970s, beta-lactam antibiotics and TMP/SMX became available for UTI therapy. [48]

  3. Outpatient parenteral antibiotic therapy - Wikipedia

    en.wikipedia.org/wiki/Outpatient_parenteral...

    Outpatient parenteral antibiotic therapy (OPAT) is used to administer non-oral antibiotics (usually intravenously) without the need for ongoing hospitalisation. OPAT is particularly useful for people who are not severely ill but do require a prolonged course of treatment that cannot be given in oral form. [ 1 ]

  4. Drug of last resort - Wikipedia

    en.wikipedia.org/wiki/Drug_of_last_resort

    It can cause severe nosebleeds, causes birth defects when taken while pregnant, is said to cause depression, hair loss and can permanently dry out the skin all over the body and is therefore not the first treatment. [12] Levosimendan — used in acutely decompensated severe chronic heart failure in situations where conventional therapy is not ...

  5. Vancomycin - Wikipedia

    en.wikipedia.org/wiki/Vancomycin

    Vancomycin is recommended to be administered in a dilute solution slowly, over at least 60 min (maximum rate of 10 mg/min for doses >500 mg) [21] due to the high incidence of pain and thrombophlebitis and to avoid an infusion reaction known as vancomycin flushing reaction. This phenomenon has been often clinically referred to as "red man syndrome".

  6. Antibiotic prophylaxis - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_prophylaxis

    In 1986, some European countries banned the use of antibiotics because of research they found that linked antibiotic use in livestock and drug resistant bacteria in humans. [11] The European Union regulated in 2006 against antibiotics for growth promotion purposes. [12] It was estimated in 2014 that over 80% of the world's antibiotic use was on ...

  7. Glycopeptide antibiotic - Wikipedia

    en.wikipedia.org/wiki/Glycopeptide_antibiotic

    Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides.Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin, avoparcin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin.

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