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Antiretroviral drugs are used to manage HIV/AIDS.Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden.. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.
In April 1995, Merck and the National Institute of Allergy and Infectious Diseases began recruiting patients for a trial examining the effects of a three drug combination of the protease inhibitor indinavir and two nucleoside analogs, [27] illustrating the substantial benefit of combining two NRTIs with a new class of antiretrovirals, protease ...
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It is safe for people over three months of age and can be used during pregnancy. [1] The medication can be taken with or without food. [ 1 ] Lamivudine is a nucleoside reverse transcriptase inhibitor and works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.
Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 Amantadine: Influenza: Influenza A virus M2 proton channel antagonist Ampligen: Avian Influenza: Immunomodulatory double-stranded RNA: Amprenavir (Agenerase) HIV Protease inhibitor (PI) Umifenovir (Arbidol) Influenza Hemagglutinin inhibitor Atazanavir: HIV PI Atripla (Efavirenz/emtricitabine ...
Lenacapavir is not approved for the prevention of HIV, but has regulatory nod in multiple countries, including U.S., for treatment of multi-drug-resistant HIV in combination with other ...
Didanosine, also called ddI, with the trade names Videx and Videx EC, was the second FDA-approved antiretroviral drug. It is an analog of adenosine. Zalcitabine, also called ddC and dideoxycytidine, has the trade name Hivid. This drug has been discontinued by the manufacturer. Stavudine, also called d4T, has trade names Zerit and Zerit XR.
Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS.It is generally recommended for use in combination with other antiretrovirals. [6]