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2. Sulodexide - Wikipedia

   en.wikipedia.org/wiki/Sulodexide

   The low molecular weight of both sulodexide fractions allows for extensive oral absorption compared to unfractionated heparin.The pharmacological effects of sulodexide differ substantially from other glycosaminoglycans and are mainly characterized by a prolonged half-life and reduced effect on global coagulation and bleeding parameters. [1]

3. Antiplatelet drug - Wikipedia

   en.wikipedia.org/wiki/Antiplatelet_drug

   Antiplatelet drugs effect may be affected by patient's medications, current medical conditions, food and supplements taken. Antiplatelet drugs effect may be increased or decreased. An increase in antiplatelet effect would increase the risk of bleeding and could cause prolonged or excessive bleeding.

4. Sarpogrelate - Wikipedia

   en.wikipedia.org/wiki/Sarpogrelate

   Sarpogrelate (former developmental code names MCI-9042, LS-187,118) is a drug which acts as an antagonist at the serotonin 5-HT 2A [1] [2] 5-HT 2B, and 5-HT 2C receptors. [3] [4] However, its affinities for the human 5-HT 2C and 5-HT 2B receptors are about one and two orders of magnitude lower than for the human 5-HT 2A receptor, respectively. [3]

5. Vortioxetine - Wikipedia

   en.wikipedia.org/wiki/Vortioxetine

   Vortioxetine was under development for the treatment of generalized anxiety disorder [59] and attention-deficit hyperactivity disorder (ADHD) [60] but development for these indications was discontinued. [61] As of August 2021, vortioxetine remains in development for the treatment of anxiety disorders, binge-eating disorder, and bipolar disorder ...

6. Antithrombotic - Wikipedia

   en.wikipedia.org/wiki/Antithrombotic

   [1] [2] Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus). In the U.S., the American College of Chest Physicians publishes clinical guidelines for clinicians for the use of these drugs to treat and prevent a variety of diseases. [citation ...

7. Direct thrombin inhibitor - Wikipedia

   en.wikipedia.org/wiki/Direct_thrombin_inhibitor

   A new sulfated β-O4 lignin (SbO4L) has been discovered which has shown a dual mechanism of action for anti-thrombosis. This SbO4L shows allosteric inhibition of thrombin for fibrinogen, while providing a competitive inhibition of thrombin interaction with platelet glycoprotein Ibα (GPIbα), thereby preventing thrombin mediated platelet ...