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10481 15408 Ensembl ENSG00000159184 ENSMUSG00000049604 UniProt Q92826 P70321 RefSeq (mRNA) NM_006361 NM_008267 RefSeq (protein) NP_006352 NP_032293 Location (UCSC) Chr 17: 48.72 – 48.73 Mb n/a PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-B13 is a protein that in humans is encoded by the HOXB13 gene. Function This gene encodes a transcription factor that belongs ...
Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body.
HOXB13: ENSG00000159184: Homeodomain: Known motif – High-throughput in vitro : TTWAYDD HOXB2: ENSG00000173917: Homeodomain: Known motif – High-throughput in vitro : TAATKR HOXB3: ENSG00000120093: Homeodomain: Known motif – High-throughput in vitro : BTAATKR HOXB4: ENSG00000182742: Homeodomain: Known motif – High-throughput in vitro ...
In molecular biology, HOXB13 antisense RNA 1 (non-protein coding), also known as HOXB13-AS1, is a long non-coding RNA. It was formerly known as PRAC2 (prostate, rectum, and colon 2). It was identified in a human prostate cDNA library, and (in humans) is found in the prostate, rectum, distal colon, and testis.
Chromosome 17 is one of the 23 pairs of chromosomes in humans.People normally have two copies of this chromosome. Chromosome 17 spans more than 84 million base pairs (the building material of DNA) and represents between 2.5 and 3% of the total DNA in cells.
These findings have been replicated, and three candidate genes with rare variants that appear to increase prostate cancer risk have been cloned: RNASEL (HPC1), which encodes ribonuclease L, MSRI, which encodes the macrophage scavenger receptor 1 and HOXB13, which encodes the homeobox B13 protein. Bailey-Wilson is focusing on identifying ...
Composite gene models of TCF/LEF genes. Extracted from Torres-Aguila et. al. (2022). [1]The TCF/LEF family (T cell factor/lymphoid enhancer factor family) is a group of genes that encode transcription factors which bind to DNA through a SOX-like high mobility group domain.
Li–Fraumeni syndrome (LFS) is a rare, autosomal dominant, hereditary disorder [1] that predisposes carriers to cancer development.It was named after two American physicians, Frederick Pei Li and Joseph F. Fraumeni Jr., who first recognized the syndrome after reviewing the medical records and death certificates of childhood rhabdomyosarcoma patients. [2]