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Metformin is a pleiotropic drug, with extensive off-target activity beyond its antidiabetic effect. Much of this has been attributed to its action on AMPK, although other mechanisms have been proposed. [221] [222] Metformin has been studied for its effects on multiple other conditions, including: Non-alcoholic fatty liver disease [223] [224] [225]
Metformin is a safe, effective and cheap, and is showing it has promise for longevity, long Covid, weight control and other issues. ... “As long as you have good renal function, the side effects ...
Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1]
Prepare for potential side effects. Taking metformin may cause unpleasant side effects like diarrhea, nausea, and an upset stomach. Taking it with food can reduce the risk.
One theory is that metformin has anti-tumor side effects because it lowers insulin levels and keeps tumor cells from multiplying. Still, more research is needed. Inside Creative House/istockphoto
Gastric adverse effects may be reduced by taking medications that suppress acid production such as proton pump inhibitors (e.g.: omeprazole and esomeprazole), or by treatment with a drug that mimics prostaglandin in order to restore the lining of the GI tract (e.g.: a prostaglandin analog misoprostol). [40]
Look out for the common side effects of metformin, which include: Indigestion. Nausea. Vomiting. Diarrhea. Flatulence. Asthenia (feeling weak or lacking energy) Stomach pain. Headache.
This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs.Non-inclusion of an herb in this list does not imply that it is free of adverse effects.
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