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Acetylcholine Acetylcholinesterase Acetylcholinesterase inhibition. Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, [1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, [2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ...
Depolarization-induced suppression of inhibition is the classical and original electrophysiological example of endocannabinoid function in the central nervous system.Prior to the demonstration that depolarization-induced suppression of inhibition was dependent on the cannabinoid CB1 receptor function, there was no way of producing an in vitro endocannabinoid mediated effect.
Pavlov introduced the ideas of strength of excitation and inhibition, as well as mobility, irradiation, and generalization in the central nervous system. [ 3 ] [ 4 ] [ 5 ] Strength of excitation was considered to be the most important of the nervous system properties by Pavlov because we are often confronted by stimuli in the environment that ...
However, scopolamine has greater effects on the central nervous system (CNS) than atropine due to its ability to cross the blood–brain barrier. [4] At higher-than-therapeutic doses, atropine and scopolamine cause CNS depression characterized by amnesia, fatigue, and reduction in rapid eye movement sleep .
In the central nervous system it is associated with PRiMA which stands for Proline Rich Membrane anchor to form symmetric form. In either case, the ColQ or PRiMA anchor serves to maintain the enzyme in the intercellular junction, ColQ for the neuromuscular junction and PRiMA for synapses.
It is one of the most widely distributed inhibitory receptors in the central nervous system and has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brainstem. [1]
Reciprocal inhibition is a neuromuscular process in which muscles on one side of a joint relax to allow the contraction of muscles on the opposite side, enabling smooth and coordinated movement. [1] This concept, introduced by Charles Sherrington , a pioneering neuroscientist , is also referred to as reflexive antagonism in some allied health ...
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord.The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts.