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Ly6 proteins are characterized by the LU domain.Typically, they contain one LU domain, but some members of the family have multiple LU domains.The LU domain consists of 60-80 AA and contains 10 cysteines arranged in a specific pattern that allows the creation of 5 disulfide bridges which in turn allow the formation of a three-fingered (3F) structural motif.
Lymphocyte antigen 6E is a protein that in humans is encoded by the LY6E gene. [5] [6] [7] Increased expression of Ly6E is associated with poor survival outcome in multiple malignancies as determined by a survey of more than 130 published clinical studies of gene expression studies on cancer tissue samples and adjacent normal tissues. [8]
Ghattas et al. state that the "intermediate" monocyte population is likely to be a unique subpopulation of monocytes, as opposed to a developmental step, due to their comparatively high expression of surface receptors involved in reparative processes (including vascular endothelial growth factor receptors type 1 and 2, CXCR4, and Tie-2) as well ...
CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene. [5] It is an LU domain and belongs to the LY6/uPAR/alpha-neurotoxin protein family. [6] CD59 attaches to host cells via a glycophosphatidylinositol (GPI) anchor.
11799 Ensembl ENSG00000089685 ENSMUSG00000017716 UniProt O15392 O70201 RefSeq (mRNA) NM_001012270 NM_001012271 NM_001168 NM_001012272 NM_001012273 NM_009689 RefSeq (protein) NP_001012270 NP_001012271 NP_001159 NP_001012273 NP_033819 Location (UCSC) Chr 17: 78.21 – 78.23 Mb Chr 11: 117.74 – 117.75 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Survivin, also called baculoviral ...
A news anchor for NBC News in Washington, D.C. is stepping away from the desk after a recent segment prompted concern from audiences. NBC4 News issued a statement on-air and on its website on ...
The fixed rate for a 15-year mortgage is 5.92%, up 8 basis points from last week's average 5.84%. These figures are lower than a year ago, when rates averaged 6.67% for a 30-year term and 5.95% ...
The expression of the vascular system begins at about 4 weeks and continues after that. [5] Other cells in which endoglin is expressed consist of monocytes, especially those transitioning into macrophages, low expression in normal smooth muscle cells, high expression vascular smooth muscle cells and in kidney and liver tissues undergoing fibrosis.
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