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Linear gingival erythema (LGE) is a periodontal disorder diagnosed based on distinct clinical characteristics. It was originally thought that LGE was directly associated with HIV, and it was thus called HIV-associated gingivitis (HIV-G).
Figure 1. Early Symptoms of HIV. The stages of HIV infection are acute infection (also known as primary infection), latency, and AIDS.Acute infection lasts for several weeks and may include symptoms such as fever, swollen lymph nodes, inflammation of the throat, rash, muscle pain, malaise, and mouth and esophageal sores.
HIV-SGD is more prevalent in HIV positive children than HIV positive adults, [4] at about 19% and 1% respectively. [1] Unlike other oral manifestations of HIV/AIDS such as Kaposi sarcoma, oral hairy leukoplakia and oral candidiasis, which decreased following the introduction of highly active antiretroviral therapy (HAART), HIV-SGD has increased.
Kaposi's Sarcoma (KS) is an extremely common disease that arises in AIDS patients and HIV-infected individuals. The condition is characterized by large purple lesions on the skin and mouth. KS presents itself differently for everyone affected by it, and its symptoms and progression varies from person to person as well. [ 5 ]
Rather than a single disease entity, periodontal disease is a combination of multiple disease processes that share a common clinical manifestation. The cause includes both local and systemic factors. The disease consists of a chronic inflammation associated with loss of alveolar bone. Advanced disease features include pus and exudates.
Periodontitis is very common, and is widely regarded as the second most common dental disease worldwide, after dental decay, and in the United States has a prevalence of 30–50% of the population, but only about 10% have severe forms. Chronic periodontitis affects about 750 million people or about 10.8% of the world population as of 2010. [86]
Necrotizing periodontal diseases are caused by a mixed bacterial infection that includes anaerobes such as P. intermedia [1] and Fusobacterium as well as spirochetes, such as Treponema. [3] Necrotizing gingivitis may also be associated with diseases in which the immune system is compromised, including HIV/AIDS. [1]
There is a clear relationship between gastroesophageal reflux disease and dental erosion and therefore can be detrimental to hard tissues i.e. teeth and also soft tissues of the mouth. [11] Crohn's disease is a patchy disease which can affect any area of the GI tract from the oral cavity to the anus. The manifestations depend on the affected area.
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