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PCBs may play a role in the development of cancers of the immune system because some tests of laboratory animals subjected to very high doses of PCBs have shown effects on the animals' immune system, and some studies of human populations have reported an association between environmental levels of PCBs and immune response. [4]
Ortho-PCBs may alter hormone regulation through disruption of the thyroid hormone transport by binding to transthyretin. [8] Coplanar PCBs are similar to dioxins and furans, both bind to the aryl hydrocarbon receptor (AhR) in organisms and may exert dioxin-like effects, in addition to the effects shared with non-coplanar PCBs.
The PCBs came from the company's two capacitor manufacturing plants at Hudson Falls and Fort Edward, New York. [1] The U.S. Environmental Protection Agency (EPA) banned the manufacture of PCBs in 1979. [9] The bulk of the PCBs in the river were manufactured by Monsanto Co. under the brand names Aroclor 1242 and Aroclor 1016. [10]
PCB-compounds, always containing low concentrations of dioxin-like PCBs and PCDFs, were synthesized for various technical purposes (see Polychlorinated biphenyls). They have entered the environment through accidents such as fires or leaks from transformers or heat exchangers, or from PCB-containing products in landfills or during incineration.
Test results conducted in the fall showed the presence of PCBs, or polychlorinated biphenyls — toxic, man-made chemicals that were banned from being produced in the United States in 1979 ...
(Reuters) -A Washington jury on Tuesday ordered Bayer to pay $100 million to four people who say they were sickened by toxic chemicals known as PCBs at a Seattle-area school, but found the company ...
The purpose statement of the agreement is "to protect human health and the environment from persistent organic pollutants." As of 2024, there are 185 countries plus the European Union have ratified the Stockholm Convention. [20] The convention and its participants have recognized the potential human and environmental toxicity of POPs.
Bioremediation of PCBs is the use of microorganisms to degrade PCBs from contaminated sites, relying on multiple microorganisms' co-metabolism. Anaerobic microorganisms dechlorinate PCBs first, and other microorganisms that are capable of doing BH pathway can break down the dechlorinated PCBs to usable intermediates like acyl-CoA or carbon ...
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