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Mammalian cells cannot use plant sterols. Normally, plant sterols are poorly absorbed from the gastrointestinal tract; fewer than 5% of plant sterols are absorbed compared to approximately 40% of cholesterol absorbed. The liver preferentially excretes plant sterols over cholesterol.
Plant sterols and stanols, when compared head-to-head in clinical trials, have been shown to equally reduce cholesterol levels. [ 41 ] [ 42 ] [ 43 ] A meta-analysis of 14 randomized, controlled trials comparing plant sterols to plant stanols directly at doses of 0.6 to 2.5 g/day showed no difference between the two forms on total cholesterol ...
The Portfolio Diet is a therapeutic plant-based diet created by British researcher David J. Jenkins in 2003 to lower blood cholesterol. [1] [2] The diet emphasizes using a portfolio of foods or food components that have been found to associate with cholesterol lowering to enhance this effect.
Plant sterols were first shown in the 1950s to lower LDLs and cholesterol. [7] Since then, numerous studies have reported the lipid-lowering effects of dietary phytosterols, including campesterol. [8] In basic research, campesterol competes with cholesterol, thus reducing the absorption of cholesterol in the human intestine. [9]
Experts recommend a plant-based diet high in soluble fiber – oatmeal, oat bran, beans, apples, peas, citrus fruits, carrots, barley, flaxseed, a gel-forming powder called psyllium, as well as ...
β-Sitosterol is widely distributed in the plant kingdom.It is found in vegetable oil, nuts, avocados, and derived prepared foods such as salad dressings. [2] Olavius algarvensis, a species of marine annelid, predominantly incorporate β-sitosterol into their cell membranes instead of cholesterol, though cholesterol is also present in said membranes.
Sterols and related compounds play essential roles in the physiology of eukaryotic organisms, and are essential for normal physiology of plants, animals, and fungi. [4] For example, cholesterol forms part of the cellular membrane in animals, where it affects the cell membrane's fluidity and serves as secondary messenger in developmental signaling.
Plant stanols are present in small amounts in human diet. Their main sources are whole-grain foods, mostly wheat and rye.The daily intake of stanols in the average western diet is about 60 mg/d, whereas the intake of plant sterols is about 150–300 mg/d and that of cholesterol is 500–800 mg/d.
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