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Remitting seronegative symmetrical synovitis with pitting edema (or sometimes RS 3 PE) is a rare syndrome identified by symmetric polyarthritis, synovitis, acute pitting edema (swelling) of the back of the hands and/or feet, and a negative serum rheumatoid factor. [2]
Polyarthritis is often caused by an auto-immune disorder such as rheumatoid arthritis, psoriatic arthritis, and lupus erythematosus, or other inflammatory rheumatic diseases, like crystal arthropathies. It can also be caused by cancer or various medications. [1] Another cause of polyarthritis is infection, which may be viral or bacterial. [1]
Moll and associates first proposed the idea of a collection of similar conditions known as seronegative spondarthritides in 1974. [61] Psoriatic arthritis , reactive arthritis , arthritis associated with inflammatory bowel disease , a subtype of juvenile idiopathic arthritis , and ankylosing spondylitis comprise the group of disorders currently ...
Though mono- and oligoarthritis have also been reported, the typical clinical presentation is a migratory non-erosive seronegative polyarthritis affecting the ankles, wrists, shoulders, hands, and fingers. [24] Usually, the arthritis appears two to three years following the surgery. [25]
In antisynthetase syndrome, arthritis is commonly described as a symmetrical, non-erosive polyarthritis of the small hands and feet that can sometimes mimic CTD-associated, rheumatoid, and seronegative inflammatory arthritis. [21] Arthritis is non-specific and occurs in about 18–55% of Idiopathic inflammatory myopathies. [21]
Seronegative spondyloarthropathy: Psoriatic arthritis; Ankylosing spondylitis; Rheumatoid arthritis: Felty's syndrome; Juvenile idiopathic arthritis; Adult-onset Still's disease; Crystal arthropathy; Gout; Chondrocalcinosis; Osteoarthritis; Hemarthrosis (joint bleeding) Synovitis is the medical term for inflammation of the synovial membrane ...
Reactive arthritis is an RF-seronegative, HLA-B27-linked arthritis [7] often precipitated by genitourinary or gastrointestinal infections. The most common triggers are intestinal infections (with Salmonella , Shigella or Campylobacter ) and sexually transmitted infections (with Chlamydia trachomatis ); [ 8 ] however, it also can happen after ...
Palindromic rheumatism is a disease of unknown cause. It has been suggested that it is an abortive form of rheumatoid arthritis (RA), since anti-cyclic citrullinated peptide antibodies (anti-CCP) and antikeratin antibodies (AKA) are present in a high proportion of patients, as is the case in rheumatoid arthritis. [6]