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To help you sort through your dog’s liver enzyme elevations, integrative veterinarian Dr. Julie Buzby explains the four main liver enzymes (ALT, AST, ALP, and GGT) and discusses the causes, diagnosis, treatment, and prognosis for high liver enzymes in dogs.
Any liver injury causes a peak increase in ALT level in dogs. The peak value of the ALT could be seen after 1-2 days of the hepatic insult or injury. The half-life of the ALT enzyme is short. So, after 2-3 days, the level of ALT that has increased due to hepatic injury starts to decrease.
If your dog has elevated liver enzymes, they may be totally normal, anorexic, vomiting, and have icterus or general malaise.
Elevated liver enzymes in dogs can be caused by a variety of conditions, both within and outside the liver. The most common causes of elevated liver enzymes in dogs are due to medications like prednisone, Cushing's disease, liver inflammation such as hepatitis, and benign, age-related changes.
What might have caused it? And, what exactly does it mean? As is often the case, there isn’t a single answer to any of these questions. So in this article, we look at some of the most common causes, the underlying conditions and the role of the liver in your dog. Table of contents. What does a dog’s liver actually do? Liver Enzymes In Dogs.
High ALT in dogs can be an indicator of liver cell damage, so it should always be a sign to look deeper for serious liver damage. ALP (Alkaline Phosphatase) ALP is an enzyme that is found in highest concentration in the liver and the bone.
Increased ALT supports hepatocellular injury, but does not provide information on liver function. Generally speaking Mild increases (up to 2-fold) can be rechecked every 2 weeks and possibly treated with nutraceutical hepatoprotectants.