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SIADH happens when your body makes excess amounts of antidiuretic hormone (ADH). SIADH causes your body to retain too much water and commonly leads to hyponatremia, which is low levels of sodium in your blood. It’s treatable.
The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a disorder of impaired water excretion caused by the inability to suppress the secretion of antidiuretic hormone (ADH) [1].
SIADH occurs when your body produces too many antidiuretic hormones. Learn about the causes, symptoms, and treatment options for this condition today.
As high-dose intravenous cyclophosphamide is given with a fluid load to prevent hemorrhagic cystitis, SIADH in such patients is a particular problem, leading to potentially fatal hyponatremia. SSRIs cause SIADH by an unknown mechanism, but people above 65 years of age are more at risk.
Causes. Symptoms. Diagnosis. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a condition in which the body makes too much antidiuretic hormone (ADH). ADH, also known as vasopressin, helps regulate how much water your body loses through urine.
Causes of SIADH include conditions that dysregulate ADH secretion in the central nervous system, tumors that secrete ADH, drugs that increase ADH secretion, among other causes. Cancer accounts for an estimated 24% of cases of SIADH, with 25% of those causes due to small cell lung cancer. [2]
Causes of SIAD include cancer, medications, pulmonary conditions, disorders of the central nervous system, postoperative state, severe nausea, and stress;...