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In case of established cancerous dissemination it is postulated that the sentinel lymph nodes are the target organs primarily reached by metastasizing cancer cells from the tumor. The sentinel node procedure (also termed sentinel lymph node biopsy or SLNB) is the identification, removal and analysis of the sentinel lymph nodes of a particular ...
To locate the draining lymph nodes or sentinel lymph nodes from a breast cancer tumour, a Technetium-99m based radiopharmaceutical is common. This may be a nanocolloid or sestamibi . [ 7 ] Although imaging with a gamma camera may also take place, the idea of a small gamma probe is that it can be used to identify lymph nodes (or other sites ...
The first draining lymph node, the "sentinel", represents an existing or non-existing tumour of an entire lymph node region. The method has been validated using radionuclides and/or blue dye for breast cancer, malignant melanoma and also gastrointestinal tumours and gives a good detection rate and sensitivity.
Melanoma metastasizes early into regional lymph nodes, so excision and analysis of so-called sentinel lymph nodes is important for treatment planning and prognosis assessment. To identify the sentinel lymph node for excision, a gamma-emitting radiotracer is injected inside the primary tumor and allowed to accumulate inside the sentinel lymph node.
Virchow's nodes take their supply from lymph vessels in the abdominal cavity, and are therefore sentinel lymph nodes of cancer in the abdomen, particularly gastric cancer, ovarian cancer, testicular cancer and kidney cancer, that has spread through the lymph vessels, and Hodgkin's lymphoma. [1]
Indocyanine green (ICG) has been widely used as a non-specific agent to detect sentinel lymph nodes during surgery. [12] ICG has the main advantage of absorbing and emitting light in the near infrared, [3] allowing detection of nodes under several centimeters of tissue.
A sentinel node biopsy can establish cancer staging of the axilla if there are positive lymph nodes present. [5] It is also less risky than performing a lymphadenectomy, having fewer side effects and a much lower chance of causing lymphedema. [5] If cancer is not present in the sentinel lymph nodes, then the axillary lymph node dissection ...
The cystic lymph node is situated at the neck of the gallbladder. [2] [4] It is invariably situated lateral to the biliary tree. [9] The node receives lymphatic drainage from the gallbladder, cystic duct, hepatic duct, and the superior portion of the common bile duct. [10] It in turn drains lymph into the hepatic lymph nodes. [2] [4]
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