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Postoperative radiation is delivered within 2–3 weeks of surgical decompression. Emergency radiation therapy (usually 20 grays in 5 fractions, 30 grays in 10 fractions or 8 grays in 1 fraction) is the mainstay of treatment for malignant spinal cord compression. It is very effective as pain control and local disease control.
Spinal cord compression is commonly found in patients with metastatic malignancy. [10] Back pain is a primary symptom of spinal cord compression in patients with known malignancy. [11] Back pain may prompt a bone scan to confirm or exclude spinal metastasis. Rapid identification and intervention of metastatic spinal cord compression is ...
Spread of cancer to the bone or spinal cord can lead to back pain. Bone is one of the most common sites of metastatic lesions. Patients typically have a history of malignancy. Common types of cancer that present with back pain include multiple myeloma, lymphoma, leukemia, spinal cord tumors, primary vertebral tumors and prostate cancer. [14]
New and more precisely defined entities include malignant melanotic nerve sheath tumor (formerly known as melanotic schwannoma) and hybrid nerve sheath tumors. [ 4 ] [ 5 ] The majority of peripheral nerve tumors are benign tumors of the nerve sheath (usually schwannomas); on rare occasions, they are metastatic tumors or originate from the nerve ...
Cross-section of the spinal cord showing the dorsal column and the anterolateral spinothalamic tracts. Surgical cutting or destruction of peripheral or central nervous tissue is now rarely used in the treatment of pain. [43] Procedures include neurectomy, cordotomy, dorsal root entry zone lesioning, and cingulotomy.
This contributes to narrowing the spinal canal and compressing the spinal cord in the corresponding region. Herniated disk due to tearing of the spinal disk over time, causes the disk to protrude and exert pressure on surrounding spinal nerve tissue. Consequent compression on the spinal cord at the cervical region causes CSM. [12]
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