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The yeast deletion project, formally the Saccharomyces Genome Deletion Project, is a project to create data for a near-complete collection of gene-deletion mutants of the yeast Saccharomyces cerevisiae. Each strain carries a precise deletion of one of the genes in the genome. This allows researchers to determine what each gene does by comparing ...
Delitto perfetto (Italian: [deˈlitto perˈfɛtto]) is a genetic technique for in vivo site-directed mutagenesis in yeast. This name is the Italian term for "perfect murder", and it refers to the ability of the technique to create desired genetic changes without leaving any foreign DNA in the genome.
In the peer-reviewed literature report, experimental results on function and interaction of yeast genes are extracted by high-quality manual curation and integrated within a well-developed database. The data are combined with quality high-throughput results and posted on Locus Summary pages which is a powerful query engine and rich genome browser.
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In 1999, the collection became a part of The United Kingdom National Culture Collection (UKNCC)., [6] which was established to co-ordinate the activities of Britain’s national collections of microbial organisms. In 2019, the collection moved to the new facility in Quadram Institute Biosciences in the Norwich Research Park where it is ...
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In yeast, the Mre11-Rad50-Xrs2 complex is recruited to DSBs early and is thought to promote bridging of the DNA ends. [16] The corresponding mammalian complex of Mre11-Rad50- Nbs1 ( MRN ) is also involved in NHEJ, but it may function at multiple steps in the pathway beyond simply holding the ends in proximity. [ 17 ]