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According to AAFCO Dog and Cat Food Nutrient Profiles (2014), the minimum amount of AA for the growth and reproduction in cat food is 0.02% on a dry matter basis or 0.05g per 1000 kcal ME per day. [9] The minimum of adult maintenance in cats is 0.02% on a dry matter basis or 0.05g per 1000 kcal ME per day. [9]
[8] [9] It was developed as a recombinant protein (rhIL-11) as the drug substance oprelvekin. The human IL-11 gene, consisting of 5 exons and 4 introns, is located on chromosome 19, [6] and encodes a 23 kDa protein. IL-11 is a member of the IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130.
Oprelvekin is recombinant interleukin eleven (IL-11), [1] a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
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The interleukin 11 receptor is a type I cytokine receptor, binding interleukin 11. It is a heterodimer composed of an interleukin 11 receptor alpha subunit and an incompletely characterized beta subunit.
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