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A benefit of midazolam is that in children it can be given in the cheek or in the nose for acute seizures, including status epilepticus. [ 22 ] [ 23 ] Drawbacks include a high degree of breakthrough seizures—due to the short half-life of midazolam—in over 50% of people treated, as well as treatment failure in 14–18% of people with ...
Midazolam is the most commonly prescribed for this use because of its strong sedative actions and fast recovery time, as well as its water solubility, which reduces pain upon injection. Diazepam and lorazepam are sometimes used. Lorazepam has particularly marked amnesic properties that may make it more effective when amnesia is the desired effect.
Chronic pain can develop from disease or injury and co-occur with acute pain. Children who experience chronic pain can have psychological effects. Caring for a child in pain may cause distress to the caregiver, may cause costs due to healthcare or lost wages from time off work, and may stop caregivers from leaving the house. [citation needed]
"Time to peak" refers to when maximum levels of the drug in the blood occur after a given dose. Benzodiazepines generally share the same pharmacological properties, such as anxiolytic , sedative , hypnotic , skeletal muscle relaxant , amnesic , and anticonvulsant effects.
Adults: 30 mg/kg (typically 1–2 g), administered by intravenous therapy over 15–30 minutes, repeated 60 minutes later. It can also be given as a 500 mg/h continuous IV infusion. Children: 20–50 mg/kg followed by a maintenance infusion at 5–10 mg/kg/h. Intravenous infusions can lead to respiratory or cardiac arrest if given too quickly. [8]
Former day care worker Melissa Calusinski has served 16 years of a 31-year prison sentence for a crime she insists she didn't commit — a murder that may not have even happened.
Growth hormone treatment is a safe and effective therapy that’s often used to treat children and adults with a deficiency in human growth hormone (also known as HGH or somatropin).
Take liquid metformin at the same time each day and with food. Just like with the tablet version, make it a habit to take liquid metformin at the same time to avoid missing doses and with food.