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Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), [1] is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002.
Galactose-α-1,3-galactose, commonly known as alpha gal and the Galili antigen, is a carbohydrate found in most mammalian cell membranes. It is not found in catarrhines , [ 1 ] including humans, who have lost the glycoprotein alpha-1,3-galactosyltransferase ( GGTA1 ) gene.
Platts-Mills is credited with the discovery of the mammalian meat allergy, after he discovered in 2002 the link between alpha-gal allergy and Lone Star tick bites. [ 6 ] Awards
From 2010 to 2022, more than 110,000 suspected cases of alpha-gal syndrome were identified, a syndrome triggered by tick bites. On Thursday, the Centers for Disease Control and Prevention ...
What is Alpha-gal syndrome? This potentially fatal condition gets its name from the molecule galactose-α-1,3-galactose (a.k.a. alpha-gal), which is found in most mammals. People with AGS can ...
Alpha-gal sounds like a sorority nickname, but it is short for the sugar galactose-alpha-1,3-galactose.
α-Galactosidase ( EC 3.2.1.22, α-GAL, α-GAL A; systematic name α-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyses the following reaction: [1] Hydrolysis of terminal, non-reducing α- D -galactose residues in α- D -galactosides, including galactose oligosaccharides, galactomannans and galactolipids
Alpha-gal may refer to: Alpha-galactosidase, an enzyme; Galactose-alpha-1,3-galactose, a carbohydrate also known as Galili antigen; Alpha-gal allergy