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Diabetic embryopathy may result in early or late spontaneous abortion and stillbirth. In maternal diabetes, 90% of pregnancy losses happen in the first trimester due to oxidative stress . Diabetic embryopathy abortions in the second-trimester are most likely due to severe birth defect , maternal metabolic derangement, placental insufficiency ...
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Congenital athymia is linked to multiple environmental etiologies. Affected fetal thymus size and other congenital anomalies like renal agenesis and butterfly vertebrae are linked to diabetic embryopathy. [9] It has been shown that babies of diabetic mothers have thymic aplasia. [10]
Aldehyde reductase is the cellular enzyme that protects the body from 3DG. Detoxification of 3DG to 3-deoxyfructose (3DF) is impaired in diabetic humans since their ratio of 3DG to 3DF in urine and plasma differs significantly from non-diabetic individuals. [9] 3DG is a teratogenic factor in diabetic embryopathy, leading to embryo malformation ...
About one third of children whose mothers are taking this drug during pregnancy typically have intrauterine growth restriction with a small head and develop minor dysmorphic craniofacial features (microcephaly and intellectual disability) and limb defects including hypoplastic nails and distal phalanges (birth defects).
The country then implemented a 21-day quarantine in Vinh Phuc province. Vietnam is a single-party state with a centralized government that is able to utilize its military resources in order to implement surveillance and contact tracing. Vietnam also has the lowest COVID-19 mortality rates (As of 2021 and 2022).
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The Vietnamese Wikipedia initially went online in November 2002, with a front page and an article about the Internet Society.The project received little attention and did not begin to receive significant contributions until it was "restarted" in October 2003 [3] and the newer, Unicode-capable MediaWiki software was installed soon after.