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  2. Metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_acidosis

    Metabolic acidosis can lead to acidemia, which is defined as arterial blood pH that is lower than 7.35. [6] Acidemia and acidosis are not mutually exclusive – pH and hydrogen ion concentrations also depend on the coexistence of other acid-base disorders; therefore, pH levels in people with metabolic acidosis can range from low to high.

  3. Acidosis - Wikipedia

    en.wikipedia.org/wiki/Acidosis

    The rate of cellular metabolic activity affects and, at the same time, is affected by the pH of the body fluids. In mammals, the normal pH of arterial blood lies between 7.35 and 7.50 depending on the species (e.g., healthy human-arterial blood pH varies between 7.35 and 7.45). [citation needed]

  4. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acid–base_homeostasis

    An acid-base diagram for human plasma, showing the effects on the plasma pH when P CO 2 in mmHg or Standard Base Excess (SBE) occur in excess or are deficient in the plasma [23] Acid–base imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.32 to 7.42 [16]).

  5. Ketoacidosis - Wikipedia

    en.wikipedia.org/wiki/Ketoacidosis

    medications, alcoholic beverages, undiagnosed diabetes Ketoacidosis is a metabolic state caused by uncontrolled production of ketone bodies that cause a metabolic acidosis . While ketosis refers to any elevation of blood ketones , ketoacidosis is a specific pathologic condition that results in changes in blood pH and requires medical attention.

  6. pH - Wikipedia

    en.wikipedia.org/wiki/PH

    Acidosis, defined by blood pH below 7.35, is the most common disorder of acid–base homeostasis and occurs when there is an excess of acid in the body. In contrast, alkalosis is characterized by excessively high blood pH. Blood pH is usually slightly alkaline, with a pH of 7.365, referred to as physiological pH in biology and medicine.

  7. Acid–base disorder - Wikipedia

    en.wikipedia.org/wiki/Acid–base_disorder

    Acid–base imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of the normal range (7.35 to 7.45). In the fetus, the normal range differs based on which umbilical vessel is sampled (umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38). [1]

  8. High anion gap metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/High_anion_gap_metabolic...

    Metabolic acidosis occurs when the body produces too much acid, or when the kidneys are not removing enough acid from the body. Several types of metabolic acidosis occur, grouped by their influence on the anion gap. The anion gap can be increased due to relatively low levels of cations other than sodium and potassium (e.g. calcium or magnesium ...

  9. Ion trapping - Wikipedia

    en.wikipedia.org/wiki/Ion_trapping

    The charge of a molecule depends upon the pH of its solution. In an acidic medium, basic drugs are more charged and acidic drugs are less charged. The converse is true in a basic medium. For example, Naproxen is a non-steroidal anti-inflammatory drug that is a weak acid (its pKa value is 5.0). The gastric juice has a pH of 2.0. It is a three ...

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