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The organic compound citrulline is an α-amino acid. [2] Its name is derived from citrullus, the Latin word for watermelon.Although named and described by gastroenterologists since the late 19th century, it was first isolated from watermelon in 1914 by Japanese researchers Yatarō Koga (古賀彌太郎) and Ryō Ōtake (大嶽了) [3] [4] and further codified by Mitsunori Wada of Tokyo ...
This is where L-citrulline supplementation comes in: Some people take L-citrulline supplements to produce L-arginine, which improves blood flow by creating nitric oxide, a gas that helps widen ...
Prolonged exposure is associated with the development of skin cancers, photoaging or premature skin aging, immune suppression, and eye diseases like cataracts. [14] [15] Given these dual effects, public health organizations emphasize the importance of striking a balance between the benefits and risks of UV exposure.
About 1% of the human population has vitiligo which causes painless distinct light-colored patches of the skin on the face, hands, and legs. Phototherapy is an effective treatment because it forces skin cells to manufacture melanin to protect the body from UV damage. Prescribed treatment is generally 3 times a week in a clinic or daily at home.
Citrulline is not one of the 20 standard amino acids encoded by DNA in the genetic code. Instead, it is the result of a post-translational modification. Citrullination is distinct from the formation of the free amino acid citrulline as part of the urea cycle or as a byproduct of enzymes of the nitric oxide synthase family.
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A systematic review examined the benefits and clinical efficacy of routine skin care activities, such as washing, bathing, and applying lotions, in acute and long-term care adult settings. The study led to a proposed 2-step program targeting adults with intact or preclinically damaged skin. [13]
We will solicit skin disease pictures from Cochrane Skin consumers globally for addition to Cochrane Skin Systematic Reviews in the Cochrane Library and Wikipedia via the social media outreach. Pictures will need to be of acceptable quality as judged by our medical and technical experts and come with:
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