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  2. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Opioid use disorders typically require long-term treatment and care with the goal of reducing the person's risks and improving their long-term physical and psychological condition. [ 106 ] First-line management involves the use of opioid replacement therapies, particularly methadone and buprenorphine/naloxone.

  3. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    A protracted withdrawal syndrome can occur with symptoms persisting for months to years after cessation of substance use. Benzodiazepines, opioids, alcohol, and any other drug may induce prolonged withdrawal and have similar effects, with symptoms sometimes persisting for years after cessation of use. Psychosis including severe anxiety and ...

  4. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    For long-acting morphine (morphine with long duration of action), withdrawal symptoms begin 12 to 48 hours after the last dose and persist for 10 to 20 days. [ 12 ] Initial symptoms include: an agitated state, feeling anxious, having muscle aches , increased tears, insomnia, discharge from the nose, more sweat production, yawning .

  5. Opioid-induced hyperalgesia - Wikipedia

    en.wikipedia.org/wiki/Opioid-induced_hyperalgesia

    Opioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids [1] such as morphine, [2] oxycodone, [3] and methadone. [4] [5] OIH is not necessarily confined to the original affected site. [6]

  6. Prescription drug addiction - Wikipedia

    en.wikipedia.org/wiki/Prescription_Drug_Addiction

    Myosis is a symptom of opiate use. [32] The signs and symptoms of opioids addiction include decreased body temperature and blood pressure, constipation, decreased sex drive, euphoria and others. [32] Conversely, people with addiction to stimulants often have increased blood pressure, heart rate, body temperature, decreased sleep and appetite. [43]

  7. Clinical Opiate Withdrawal Scale - Wikipedia

    en.wikipedia.org/wiki/Clinical_Opiate_Withdrawal...

    Clinical Opiate Withdrawal Scale (COWS) is a method used by registered practitioners to measure the severity of a patient's opioid withdrawal symptoms. This method consists of a series of 11 topics each comprising 4 - 5 common symptoms experienced by a patient undergoing opioid withdrawal. In each topic a rank is given depending on what the ...

  8. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Higher doses of prescription opioids as well as long acting formulations are associated with an increased risk of overdose. [24] In those on long term opioid treatment for chronic pain, daily morphine equivalents greater than 200 mg were associate with death from opioid related causes (including overdose) in 3.8% of men and 2.2% of women. [24]

  9. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    The term "cold turkey" is used to describe the sudden cessation of use of a substance and the ensuing physiologic manifestations. The symptoms from withdrawal may be even more dramatic when the drug has masked prolonged malnutrition , disease, chronic pain , infections (common in intravenous drug use), or sleep deprivation , conditions that ...

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