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Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA). RNA and deoxyribonucleic acid (DNA) are nucleic acids.
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The RNA chain is synthesized from the 5' end to the 3' end as the 3'-hydroxyl group of the last ribonucleotide in the chain acts as a nucleophile and launches a hydrophilic attack on the 5'-triphosphate of the incoming ribonucleotide, releasing pyrophosphate as a by-[6] product. Due to the physical properties of the nucleotides, the backbone of ...
Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7 (for the phosphorolytic enzymes) and 3.1 (for the hydrolytic enzymes) classes of enzymes.
5' cap structure. A 5' cap (also termed an RNA cap, an RNA 7-methylguanosine cap, or an RNA m 7 G cap) is a modified guanine nucleotide that has been added to the "front" or 5' end of a eukaryotic messenger RNA shortly after the start of transcription. The 5' cap consists of a terminal 7-methylguanosine residue that is linked through a 5'-5 ...
Small RNA that is activated by SgrR in Escherichia coli during glucose-phosphate stress shRNA: short hairpin RNA - siRNA: small interfering RNA - SL RNA spliced leader RNA multiple families: SmY RNA: mRNA trans-splicing RF01844: Small nuclear RNAs found in some species of nematode worms, thought to be involved in mRNA trans-splicing snoRNA ...
A short 20-nucleotide RNA variant ribozyme was identified that self-reproduces via template directed ligation of two 10 nucleotide oligomers. [38] This minimal kind of RNA self-reproduction was discovered in a random pool of oligmers, and may represent an early step in the emergence of an RNA based genetic system from primordial components. [38]
The standard RNA codon table organized in a wheel A codon table can be used to translate a genetic code into a sequence of amino acids . [ 1 ] [ 2 ] The standard genetic code is traditionally represented as an RNA codon table, because when proteins are made in a cell by ribosomes , it is messenger RNA (mRNA) that directs protein synthesis .