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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4.. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
Phage injecting its genome into bacterial cell An electron micrograph of bacteriophages attached to a bacterial cell. These viruses are the size and shape of coliphage T1. Phage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections.
The basic experimental toolkit of phage "organismal" ecology consists of the single-step growth (or one-step growth; [12]) experiment and the phage adsorption curve. [13] Single-step growth is a means of determining the phage latent period ( example ), which is approximately equivalent (depending on how it is defined) to the phage period of ...
The average virion is about one one-hundredth the linear size of the average bacterium. A teaspoon of seawater typically contains about fifty million viruses. [6] Most of these viruses are bacteriophages which infect and destroy marine bacteria and control the growth of phytoplankton at the base of the marine food web. Bacteriophages are ...
Several bacteriophages contain toxin genes that become incorporated into the host bacteria genome through infection and render the bacteria toxic. [9] Many well known bacterial toxins are produced from specific strains of the bacteria species that have obtained toxigenicity through lysogenic conversion, pseudolysogeny, or horizontal gene ...
Escherichia virus T4 is a species of bacteriophages that infect Escherichia coli bacteria. It is a double-stranded DNA virus in the subfamily Tevenvirinae of the family Straboviridae . T4 is capable of undergoing only a lytic life cycle and not the lysogenic life cycle .
In a 1945 study by Demerec and Fano, [4] T7 was used to describe one of the seven phage types (T1 to T7) that grow lytically on Escherichia coli. [5] Although all seven phages were numbered arbitrarily, phages with odd numbers, or T-odd phages, were later discovered to share morphological and biochemical features that distinguish them from T-even phages. [6]
Virophages need to have a co-infecting virus in order for them to replicate. The virophages do not have the necessary enzymes to replicate on their own. Virophages use the giant viral replication machinery to replicate their own genomes and continue their existence. The host range for virophages include giant viruses with double stranded DNA ...