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[h] The authors conclude that if replication is defined by a subsequent study finding a sufficiently similar effect size to the original, replication success is not likely even if replications have very large sample sizes. Importantly, this occurs even if replications are direct or exact since heterogeneity nonetheless remains relatively high ...
The growth of metascience and the recognition of a scientific replication crisis have bolstered the paper's credibility, and led to calls for methodological reforms in scientific research. [8] [9] In commentaries and technical responses, statisticians Goodman and Greenland identified several weaknesses in Ioannidis' model.
Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.
In engineering, science, and statistics, replication is the process of repeating a study or experiment under the same or similar conditions. It is a crucial step to test the original claim and confirm or reject the accuracy of results as well as for identifying and correcting the flaws in the original experiment. [ 1 ]
Credit - Photo-Illustration by TIME; Capelle.r/Getty Images; Artfully79/Getty Images. W hen the German philosopher Immanuel Kant puzzled over why nature looks beautiful to us, he considered the ...
Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes. Due to this problem, DNA is lost in each replication cycle from the end of the chromosome.
1. "The replication crisis most severely affects the social and medical sciences." This statement is not supported by the inline citation that follows it, as the source only says that replication is a problem in social and medical sciences, but does not necessarily say that it is most severe in social and medical sciences.
The European Union and Australia have failed to conclude talks on a planned free trade agreement after differences remained unresolved, notably on agricultural products, the two sides said on Tuesday.