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The replication crisis [a] is an ... publications and decreases when another lab fails to replicate its results. ... conclude that if replication is defined by a ...
The replication fork consists of a group of proteins that influence the activity of DNA replication. In order for the replication fork to stall, the cell must possess a certain number of stalled forks and arrest length. The replication fork is specifically paused due to the stalling of helicase and polymerase activity, which are linked together ...
Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.
Slipped strand mispairing (SSM, also known as replication slippage) is a mutation process which occurs during DNA replication. It involves denaturation and displacement of the DNA strands, resulting in mispairing of the complementary bases. Slipped strand mispairing is one explanation for the origin and evolution of repetitive DNA sequences. [1]
Replication of DNA always begins at an origin of replication. In yeast, the origins contain autonomously replicating sequences (ARS), distributed throughout the chromosome about 30 kb from each other. They allow replication of DNA wherever they are placed. Each one is 100-200 bp long, and the A element is one of the most conserved stretches.
The "Yellowstone" Season 5 finale just left viewers wanting more and they may just get their wish.On Dec. 15, the popular series wrapped up its fifth season with an explosive finale that killed ...
The growth of metascience and the recognition of a scientific replication crisis have bolstered the paper's credibility, and led to calls for methodological reforms in scientific research. [8] [9] In commentaries and technical responses, statisticians Goodman and Greenland identified several weaknesses in Ioannidis' model.
Most Americans in a new poll said they probably won’t get an updated COVID-19 vaccine. The Pew Research Center survey found 60 percent said they are “probably not” going to “get an updated ...