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Idiopathic orbital inflammatory (IOI) disease refers to a marginated mass-like enhancing soft tissue involving any area of the orbit. It is the most common painful orbital mass in the adult population, and is associated with proptosis , cranial nerve palsy ( Tolosa–Hunt syndrome ), uveitis , and retinal detachment .
Tolosa–Hunt syndrome is a rare disorder characterized by severe and unilateral headaches with orbital pain, along with weakness and paralysis (ophthalmoplegia) of certain eye muscles (extraocular palsies). [1] In 2004, the International Headache Society provided a definition of the diagnostic criteria which included granuloma. [2]
IgG4-related ophthalmic disease (IgG4-ROD) is the recommended term to describe orbital (eye socket) manifestations of the systemic condition IgG4-related disease, [2] which is characterised by infiltration of lymphocytes and plasma cells and subsequent fibrosis in involved structures. It can involve one or more of the orbital structures.
Tenon's capsule may be affected by a disease called idiopathic orbital inflammation, a condition of unknown etiology that is characterized by inflammation of one or more layers of the eye. The disease is also known as orbital inflammatory pseudotumor, and sometimes may only affect the lacrimal gland or the extraocular muscles. [2]
Trochleitis was first identified in 1984 by Tychsen, et al. in a study of thirteen patients with orbital pain and point tenderness over the trochlear region. Previously, the trochleitis syndrome had been included in the broad category of idiopathic orbital inflammation (also called orbital pseudotumor).
Examples include sarcoidosis, thyroid eye disease, and orbital pseudotumor. Diagnosis. Dacryoadenitis can be diagnosed by examination of the eyes and lids.
The disease was renamed benign intracranial hypertension in 1955 to distinguish it from intracranial hypertension due to life-threatening diseases (such as cancer); [30] however, this was also felt to be misleading because any disease that can blind someone should not be thought of as benign, and the name was therefore revised in 1989 to ...
IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, various degrees of fibrosis (scarring) and a usually prompt response to oral steroids.