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Angiopathy is the generic term for a disease of the blood vessels (arteries, veins, and capillaries). [1] This also refers to the condition of damage or rupture of small blood vessels. The best known and most prevalent angiopathy is diabetic angiopathy, a common complication of chronic diabetes.
Atherosclerosis is the most common cause of stenosis (narrowing of the blood vessels) of the heart's arteries and, hence, angina pectoris. Some people with chest pain have normal or minimal narrowing of heart arteries; in these patients, vasospasm is a more likely cause for the pain, sometimes in the context of Prinzmetal's angina and syndrome X.
The increase in pulse pressure may result in increased damage to blood vessels in target organs such as the brain or kidneys. [23] [24] This effect may be exaggerated if the increase in arterial stiffness results in reduced wave reflection and more propagation of the pulsatile pressure into the microcirculation. [23]
People with coronary artery disease, or narrowing of the blood vessels supplying their heart, may develop symptoms such as: Chest pain that often gets worse with stress or physical activity ...
Severe disease may in rare cases lead to complications, specifically skin sores or gangrene. [2] About 4% of people have the condition. [3] Onset of the primary form is typically between ages 15 and 30 and occurs more frequently in females. [3] [4] The secondary form usually affects older people. [4] Both forms are more common in cold climates. [4]
This explains why people with medical conditions that cause an increased core body temperature like multiple sclerosis (MS), epilepsy, anxiety, and head trauma experience excessive yawning ...
Lesions reflect leakage of plasma components across vascular endothelium and excessive extracellular matrix production by smooth muscle cells, usually secondary to hypertension. [ 11 ] Hyaline arteriolosclerosis is a major morphologic characteristic of benign nephrosclerosis , in which the arteriolar narrowing causes diffuse impairment of renal ...
Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries.This is a chronic inflammatory disease involving many different cell types and driven by elevated levels of cholesterol in the blood. [9]