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Gantenerumab is a monoclonal antibody for the treatment of Alzheimer's disease being developed by Hoffmann-La Roche pharmaceuticals. [1] [2] Gantenerumab binds to and clears aggregated beta amyloid fibers. [3] A phase III clinical trial of gantenerumab was stopped early because of a lack of efficacy. [4]
Current Alzheimer Research is a peer-reviewed medical journal covering the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer's disease. [ 3 ] Abstracting and indexing
Psychological therapies for dementia are starting to gain some momentum. [when?] Improved clinical assessment in early stages of Alzheimer's disease and other forms of dementia, increased cognitive stimulation of the elderly, and the prescription of drugs to slow cognitive decline have resulted in increased detection in the early stages.
This trial proves that Alzheimer’s disease can be treated.” NEW DATA: Topline data from the confirmatory Phase 3 CLARITY AD trial is now available for our investigational anti-amyloid-beta ...
Regarding incidence, cohort longitudinal studies (studies where a disease-free population is followed over the years) provide rates between 10 and 15 per thousand person-years for all dementias and 5–8 for AD, [235] [236] which means that half of new dementia cases each year are Alzheimer's disease. Advancing age is a primary risk factor for ...
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A new study in mice modified to develop Alzheimer’s symptoms has shown that treatment with a synthetic peptide can reduce this protein buildup and restore memory and learning functions.
Aducanumab, sold under the brand name Aduhelm, is an anti-amyloid drug designed to treat Alzheimer's disease. [2] [3] It is a monoclonal antibody [3] [2] that targets aggregated forms (plaque) [4] [5] of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup.
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