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Klippel–Trénaunay syndrome, formerly Klippel–Trénaunay–Weber syndrome [1] and sometimes angioosteohypertrophy syndrome and hemangiectatic hypertrophy, [2] is a rare congenital medical condition in which blood vessels and/or lymph vessels fail to form properly.
Parkes Weber syndrome (PWS) is a congenital disorder of the vascular system. It is an extremely rare condition, and its exact prevalence is unknown. [1] [2] [3] It is named after British dermatologist Frederick Parkes Weber, who first described the syndrome in 1907. [4] In the body, the vascular system consists of arteries, veins and capillaries.
Syndromes associated with capillary malformations are: Sturge–Weber syndrome and Klippel–Trénaunay syndrome. [14] Capillary malformations can be treated with IPL-(Intensed-pulsed-light)-therapy or surgical resection. [3]
Maurice Klippel (30 May 1858 – 20 July 1942) was a French physician, for whom the conditions Klippel–Feil syndrome and Klippel–Trénaunay–Weber syndrome are named. He was born in Mulhouse , Haut-Rhin and studied medicine in Paris , earning his doctorate in 1889.
These include Klippel–Trenaunay syndrome, macrocephaly-capillary malformation syndrome, cutis marmorata telangiectatica congenita, CLOVES syndrome (congenital lipomatous overgrowth, vascular malformation, epidermal nevus, scoliosis), and Proteus syndrome.
Children with some overgrowth syndromes such as Klippel–Trénaunay syndrome can be readily detectable at birth. [3] In contrast, other overgrowth syndromes such as Proteus syndrome usually present in the postnatal period, characteristically between the second and third year of life. [ 2 ]
4. Stress. Stress can lead to overeating, eating high-calorie or high-fat foods, and sleep loss. When you’re stressed, the stress hormone cortisol reduces your brain’s sensitivity to leptin ...
It is therefore useful for longer and larger veins. Experts in foam sclerotherapy have created “tooth paste” like thick foam for their injections, which has revolutionized the non-surgical treatment of varicose veins [23] and venous malformations, including Klippel–Trénaunay syndrome. [24]