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KTS is a complex syndrome, and no single treatment is applicable for everyone. Treatment is decided on a case-by-case basis with the individual's doctors. [citation needed] At present, many of the symptoms may be treated, but there is no cure for Klippel–Trenaunay syndrome. [14]
Treatment of PROS diseases is variable and depends on the specific disease. Curative treatment does not exist and most treatments are given to control symptoms. Overgrowth and malformations of solid tissues can be treated with surgery. Sclerotherapy can be used to treat vascular malformations. [5]
It is therefore useful for longer and larger veins. Experts in foam sclerotherapy have created “tooth paste” like thick foam for their injections, which has revolutionized the non-surgical treatment of varicose veins [23] and venous malformations, including Klippel–Trénaunay syndrome. [24]
Syndromes associated with capillary malformations are: Sturge–Weber syndrome and Klippel–Trénaunay syndrome. [14] Capillary malformations can be treated with IPL-(Intensed-pulsed-light)-therapy or surgical resection. [3]
Children with some overgrowth syndromes such as Klippel–Trénaunay syndrome can be readily detectable at birth. [3] In contrast, other overgrowth syndromes such as Proteus syndrome usually present in the postnatal period, characteristically between the second and third year of life. [ 2 ]
PWS is often confused with Klippel–Trénaunay syndrome (KTS). These two diseases are similar, but they are distinct. PWS occurs because of vascular malformation that may or may not be because of genetic mutations, whereas Klippel-Trénaunay syndrome is a condition in which blood vessels and or lymph vessels do not form properly. [7]
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These include Klippel–Trenaunay syndrome, macrocephaly-capillary malformation syndrome, cutis marmorata telangiectatica congenita, CLOVES syndrome (congenital lipomatous overgrowth, vascular malformation, epidermal nevus, scoliosis), and Proteus syndrome.