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Respiratory sounds, also known as lung sounds or breath sounds, are the specific sounds generated by the movement of air through the respiratory system. [1] These may be easily audible or identified through auscultation of the respiratory system through the lung fields with a stethoscope as well as from the spectral characteristics of lung sounds. [2]
Whooping cough (/ ˈ h uː p ɪ ŋ / or / ˈ w uː p ɪ ŋ /), also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. [1] [10] Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. [1]
Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin , adenylate cyclase toxin , filamentous haemagglutinin , pertactin , fimbria , and tracheal cytotoxin .
Pertussis toxin (PT) is a protein-based AB 5-type exotoxin produced by the bacterium Bordetella pertussis, [2] which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. [ 3 ]
The cough reflex occurs when stimulation of cough receptors in the respiratory tract by dust or other foreign particles produces a cough, which causes rapidly moving air which usually remove the foreign material before it reaches the lungs.
A cough is a sudden expulsion of air through the large breathing passages which can help clear them of fluids, irritants, foreign particles and microbes.As a protective reflex, coughing can be repetitive with the cough reflex following three phases: an inhalation, a forced exhalation against a closed glottis, and a violent release of air from the lungs following opening of the glottis, usually ...
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