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An HPV infection is caused by the human papillomavirus, a DNA virus from the papillomavirus family. [8] [9] Over 200 types have been described. [10] An individual can become infected with more than one type of HPV, [11] and the disease is only known to affect humans.
There are about 130 known types of human papillomaviruses. [9] HPV infects the squamous epithelium, usually of the skin or genitals, but each HPV type is typically only able to infect a few specific areas of the body. Many HPV types can produce a benign growth, often called a "wart" or "papilloma", in the area they infect. [10]
Cervarix is a vaccine against certain types of cancer-causing human papillomavirus (HPV). Cervarix is designed to prevent infection from HPV types 16 and 18, that cause about 70% of cervical cancer cases. [6] These types also cause most HPV-induced genital and head and neck cancers.
Gardasil is an HPV vaccine for use in the prevention of certain strains of human papillomavirus (HPV). [10] [7] [8] [9] [11] It was developed by Merck & Co. [12] High-risk human papilloma virus (hr-HPV) genital infection is the most common sexually transmitted infection among women. [13]
US incidence of HPV infection has increased between 1975 and 2006. [29] About 80% of those infected are between the ages of 17 and 33. [29] Although treatments can remove warts, they do not remove the HPV, so warts can recur after treatment (about 50–73% of the time [33]). Warts can also spontaneously regress (with or without treatment). [29]
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The human papillomavirus (HPV) is the most common STI in the United States. [64] There are more than 40 different strands of HPV and many do not cause any health problems. In 90% of cases, the body's immune system clears the infection naturally within two years. [65]