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The severity and location of the deformities depended on how many days into the pregnancy the mother was before beginning treatment; thalidomide taken on the 20th day of pregnancy caused central brain damage, day 21 would damage the eyes, day 22 the ears and face, day 24 the arms, and leg damage would occur if taken up to day 28.
Thalidomide is a known human teratogen and carries an extremely high risk of severe, life-threatening birth defects if administered or taken during pregnancy. [6] It causes skeletal deformities such as amelia (absence of legs and/or arms), absence of bones, and phocomelia (malformation of the limbs).
Survivors of the harmful morning sickness drug thalidomide were in the public gallery Wednesday when Australia’s Parliament made a national apology to them on the 62nd anniversary of the drug ...
McBride published a letter in The Lancet, in December 1961, noting a large number of birth defects in children of patients who were prescribed thalidomide, [9] after a midwife named Sister Pat Sparrow first suspected the drug was causing birth defects in the babies of patients under his care at Crown Street Women's Hospital in Sydney. [10]
Thalidomide was the active ingredient in a sedative widely distributed to many mothers in Australia and around the world in the early 1960s. It was found to cause malformation of limbs, facial ...
“The thalidomide tragedy is a dark chapter in the history of our nation and the world,” Australian prime minister Anthony Albanese said on Monday. ... The drug caused malformation of limbs ...
Frances Kathleen Oldham Kelsey CM (née Oldham; July 24, 1914 – August 7, 2015) was a Canadian-American [1] pharmacologist and physician. As a reviewer for the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding the drug's safety. [2]
‘The thalidomide tragedy is a dark chapter in the history of our nation and the world’ Australia to issue national apology to citizens affected by ‘Thalidomide birth defects’ Skip to main ...