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There is little modern clinical research on Dioscorea villosa, and the one study of a wild yam-containing cream for menopausal symptoms failed to find any value from this therapy. [18] According to the American Cancer Society , there is no evidence to support wild yam or diosgenin being either safe or effective in humans.
Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam species, such as the Kokoro. It is also present in smaller amounts in a number of other species.
Some of the ingredients included in supplements are carcinogenic, including don quai. [1]: 1331 By altering the body's hormonal levels, certain ingredients, including zearalenone, may reduce fertility. [9] One ingredient, kava, may cause liver damage. [2]: 1347 Black cohosh has been shown to have no estrogenic effect in vivo or in vitro.
Bioidentical hormones were first used for menopausal symptom relief in the 1930s, [2] after Canadian researcher James Collip developed a method to extract an orally active estrogen from the urine of pregnant women and marketed it as the active agent in a product called Emmenin. [3]
Before this development, natural hormones were extracted from animal sources, such as urine from pregnant mares or women, or from bull testes; prices were consequently very high. With the development of the process of Marker degradation which allowed the production of hormones from vegetable saponin sources, Marker began a search for a plant ...
Dioscorea alata – also called ube (/ ˈ uː b ɛ,-b eɪ /), ubi, purple yam, or greater yam, among many other names – is a species of yam (a tuber). The tubers are usually a vivid violet - purple to bright lavender in color (hence the common name), but some range in color from cream to plain white.
Dioscorea dregeana, the wild yam, is a perennial creeper that is native to the eastern parts of southern Africa. [1] It is commonly used and traded as a traditional medicine, or muti . [ 1 ]
Dioscorea bulbifera (commonly known as the air potato, air yam, bitter yam, cheeky yam, potato yam, [2] aerial yam, [3] and parsnip yam [4]) is a species of true yam in the yam family, Dioscoreaceae. It is native to Africa, Asia and northern Australia. [ 1 ]
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