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Flux is the net movement of particles across a specified area in a specified period of time. [1] The particles may be ions or molecules, or they may be larger, like insects, muskrats or cars. The units of time can be anything from milliseconds to millennia. Flux is not the same as velocity or speed nor is it the same as density or concentration.
Flux is therefore of great interest in metabolic network modelling, where it is analysed via flux balance analysis and metabolic control analysis. In this manner, flux is the movement of matter through metabolic networks that are connected by metabolites and cofactors , and is therefore a way of describing the activity of the metabolic network ...
Since one of the assumptions of the GHK flux equation is that the ions move independently of each other, the total flow of ions across the membrane is simply equal to the sum of two oppositely directed fluxes. Each flux approaches an asymptotic value as the membrane potential diverges from zero. These asymptotes are
Flux (biology), movement of a substance between compartments; Flux (metabolism), the rate of turnover of molecules through a metabolic pathway; 4-Fluoroamphetamine (4-FA; PAL-303; "Flux"), a central nervous system stimulant with quasi-amphetamine effects; Dysentery, or other diseases called "flux", which cause the loss of fluid by diarrhea or ...
Fluxomics describes the various approaches that seek to determine the rates of metabolic reactions within a biological entity. [1] While metabolomics can provide instantaneous information on the metabolites in a biological sample, metabolism is a dynamic process. [2]
The flux control coefficient, instead, measures how much influence a given step has on the steady-state flux. A step with a high flux control coefficient means that changing the activity of the step (by changing the expression level of the enzyme) will have a large effect on the steady-state flux through the pathway and vice versa.
[9] [10] [11] [7] Biology is the main driver of O 2 flux on modern Earth, and the evolution of oxygenic photosynthesis by bacteria, which is discussed as part of the Great Oxygenation Event, is thought to be directly responsible for the conditions permitting the development and existence of all complex eukaryotic metabolism. [12] [13] [14]
Given a flux according to the electromagnetism definition, the corresponding flux density, if that term is used, refers to its derivative along the surface that was integrated. By the Fundamental theorem of calculus , the corresponding flux density is a flux according to the transport definition.