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The Centers for Disease Control and Prevention issued a health advisory Tuesday alerting authorities, health care providers and the public of the increased risk of dengue fever infections in the ...
It is indicated for the prevention of dengue disease in individuals four years of age and older, and can be administered to people who have not been previously infected with dengue. It is a live attenuated vaccine containing the four serotypes of dengue virus, administered subcutaneously as two doses three months apart.
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
In a small proportion of cases the disease develops into the life-threatening dengue hemorrhagic fever, resulting in hemorrhage, thrombocytopenia and blood plasma leakage, or into dengue shock syndrome, where shock occurs. Dengue is transmitted by several species of mosquito within the genus Aedes, principally A. aegypti.
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]