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Progressive retinal atrophy (PRA) is a group of genetic diseases seen in certain breeds of dogs and, more rarely, cats. Similar to retinitis pigmentosa in humans, [ 1 ] it is characterized by the bilateral degeneration of the retina , causing progressive vision loss culminating in blindness.
One such condition is progressive retinal atrophy, or PRA, which affects the light-sensitive cells at the back of the eye. It affects over 100 breeds, can be caused by multiple different genetic ...
Progressive retinal atrophy (PRA) is a genetic disease of the retina that occurs bilaterally and is seen in certain breeds of dogs. It causes progressive vision loss culminating in blindness. [63] Retinal dysplasia is an eye disease affecting the retina. It is usually a nonprogressive disease and can be caused by viral infections, drugs ...
Sudden acquired retinal degeneration syndrome (SARDS) is a disease in dogs causing sudden blindness. It can occur in any breed, but female dogs may be predisposed. [1] Approximately 4000 cases are seen in the United States annually. [2]
Cataracts typically occur when proteins break down in the lens of a dog's eye and clump together, obstructing the passage of light. [1] [2] There are several reasons cataracts may occur in dogs, such as heredity, trauma, aging, diabetes, glaucoma, and progressive retinal atrophy.
Canine-specific eye diseases include progressive retinal atrophy, Collie eye anomaly, sudden acquired retinal degeneration, and cherry eye. Injury to the eye can result in corneal ulcers. The frequency of bilateral glaucoma with a genetic base in purebred dogs is higher than in any species except humans. [24]
Retinal detachment occurs with complete retinal dysplasia, and is accompanied by blindness in that eye. Cataracts or glaucoma can also occur secondary to retinal dysplasia. Other causes of retinal dysplasia in dogs include infection with canine adenovirus or canine herpesvirus , or radiation of the eye in newborns.
Age-Related Macular Degeneration is a degenerative maculopathy associated with progressive sight loss. It is characterised by changes in pigmentation in the Retinal Pigment Epithelium, the appearance of drusen on the retina of the eye and choroidal neovascularization. AMD has two forms; 'dry' or atrophic/non-exudative AMD, and 'wet' or ...