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These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
[2] [3] It has also been used to treat male infertility, although this use is controversial. [2] [4] [5] It is taken by mouth. [2] Side effects of mesterolone include symptoms of masculinization like acne, scalp hair loss, increased body hair growth, voice changes, and increased sexual desire. [2] It has no risk of liver damage.
In any case, common side effects of antiandrogens in men include breast tenderness, breast enlargement, feminization, hot flashes, sexual dysfunction, infertility, and osteoporosis. In women, antiandrogens are much better tolerated , and antiandrogens that work only by directly blocking androgens are associated with minimal side effects.
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
Other significant adverse effects of testosterone supplementation include acceleration of pre-existing prostate cancer growth in individuals who have undergone androgen deprivation; increased hematocrit, which can require venipuncture in order to treat; and, exacerbation of sleep apnea. [28]
5-ARIs are generally well tolerated in both men and women and produce few side effects. [ 19 ] [ 20 ] However, they have been found to have some risks in studies with men, including slightly increased risks of decreased libido , erectile dysfunction , ejaculatory dysfunction , infertility , breast tenderness , gynecomastia , depression ...
What you really need to watch out for are the more serious side effects, which may include: Eye problems, like blurred vision, retinitis pigmentosa, or vision loss. Chest pain. Loss of hearing ...
Since infertility increases the risk of ovarian cancer, fertility drugs have been used to combat this but the cancer risks are still not completely known. [27] As of 2019, [update] there have been studies that have shown the risk of developing ovarian cancer is higher when taking fertility medications.
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