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Diphtheria is an infection caused by the bacterium Corynebacterium diphtheriae. [2] Most infections are asymptomatic or have a mild clinical course , but in some outbreaks, the mortality rate approaches 10%. [ 1 ]
Corynebacterium diphtheriae [a] is a Gram-positive pathogenic bacterium that causes diphtheria. [2] It is also known as the Klebs–Löffler bacillus because it was discovered in 1884 by German bacteriologists Edwin Klebs (1834–1912) and Friedrich Löffler (1852–1915). [3]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
In Nigeria, only 42% of children under 15 years old are fully protected from diphtheria, according to a government survey, while Guinea has a 47% immunization rate — both far below the 80–85% ...
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The post West Africa responds to huge diphtheria outbreaks by targeting unvaccinated populations appeared first on TheGrio. ... Biden will visit New Orleans on Monday in the wake of the deadly ...
Diphtheria toxin is a single polypeptide chain of 535 amino acids consisting of two subunits linked by disulfide bridges, known as an A-B toxin.Binding to the cell surface of the B subunit (the less stable of the two subunits) allows the A subunit (the more stable part of the protein) to penetrate the host cell.
Fortunately, whooping cough is preventable by a series of vaccines that many people receive as an infant called DTaP - which stands for Diphtheria, Tetanus, and Pertussis.