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Between June 1942 and February 1943, 714 cases of diphtheria were recorded at Sham Shui Po Barracks, resulting in 112 deaths because the Imperial Japanese Army did not release supplies of anti-diphtheria serum. [61] In 1943, diphtheria outbreaks accompanied war and disruption in Europe. The 1 million cases in Europe resulted in 50,000 deaths.
Originally a major cause of childhood mortality, diphtheria has been almost entirely eradicated due to the vigorous administration of the diphtheria vaccination in the 1910s. [7] Diphtheria is no longer transmitted as frequently due to the development of the vaccine, DTaP. Although diphtheria outbreaks continue to occur, this is often in ...
Diphtheria toxin is extraordinarily potent. [4] The lethal dose for humans is about 0.1 μg of toxin per kg of body weight. Death occurs through necrosis of the heart and liver. [10] Diphtheria toxin has also been associated with the development of myocarditis. Myocarditis secondary to diphtheria toxin is considered one of the biggest risks to ...
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Then in the 1970s the diphtheria, tetanus, and whooping cough jab was linked to brain injury in children, before later being found safe. Certain decisions by the government prompted some people to ...
The Australian state of Queensland experienced frequent diphtheria outbreaks in the early 20th century, with up to 2,000 cases reported per annum. [1] In the city of Bundaberg there were 130 cases reported in 1926 and 89 cases in 1927. [2] The disease had a high mortality rate and in a number of years was the leading cause of childhood death in ...
A company called Tomorrow Biostasis is focusing on human cryopreservation in the hopes it can eventually reverse death. The new Berlin startup has already preserved the bodies of about 10 deceased ...
Jim Vintage 1895 vial of diphtheria antitoxin. On October 2, 1901, a former milk wagon horse named Jim showed signs that he had contracted tetanus and was euthanized. He was used to produce serum containing diphtheria antitoxin (antibodies against diphtheria toxin). Jim produced over 30 US quarts (7.5 US gallons; 28.5 litres) of diphtheria ...