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Dyslipidemia is a metabolic disorder characterized by abnormally high or low amounts of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [1] Dyslipidemia is a risk factor for the development of atherosclerotic cardiovascular diseases , [ 1 ] which include coronary artery disease ...
Dyslipidemia. Dyslipidemia is when the lipids in your blood are too high or too low. Estimates suggest that 53 percent of adults in the U.S. have lipid abnormalities.. Lipids are a type of fat ...
Hyperlipidemia represents a subset of dyslipidemia and a superset of hypercholesterolemia. Hyperlipidemia is usually chronic and requires ongoing medication to control blood lipid levels. [3] Lipids (water-insoluble molecules) are transported in a protein capsule. [4] The size of that capsule, or lipoprotein, determines its density. [4]
Combined hyperlipidemia (or -aemia) is a commonly occurring form of hypercholesterolemia (elevated cholesterol levels) characterised by increased LDL and triglyceride concentrations, often accompanied by decreased HDL.
[3] [4] [5] Although less effective in lowering LDL levels, the ability of fibrates to increase HDL and lower triglyceride levels seems to reduce insulin resistance when the dyslipidemia is associated with other features of the metabolic syndrome (hypertension and diabetes mellitus type 2). [6] They are therefore used in many hyperlipidemias ...
Signs of familial dysbetaproteinemia include xanthoma striatum palmare (orange or yellow discoloration of the palms) and tuberoeruptive xanthomas over the elbows and knees.
[105] [109] [111] [112] [113] Warner-Lambert management was concerned that atorvastatin was a me-too version of rival Merck & Co.'s orphan drug lovastatin (brand name Mevacor). Mevacor, which was first marketed in 1987, was the industry's first statin and Merck's synthetic version – simvastatin – was in the advanced stages of development ...
Stress is a life event or series of events that disrupt a person's psychological equilibrium and may catalyze the development of a disorder. [3] Thus the diathesis-stress model serves to explore how biological or genetic traits ( diatheses ) interact with environmental influences ( stressors ) to produce disorders such as depression, anxiety ...